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Over titration is a real issue and yes it can do harm. I would rather cut off my left leg then have to agree with an RT but alas just this one time. and to all my RT pals..im just kidding I would only cut off my finger.
Over titration is a real issue and yes it can do harm. I would rather cut off my left leg then have to agree with an RT but alas just this one time. and to all my RT pals..im just kidding I would only cut off my finger.
Overtitration is a nonissue.
When pressure choices are put in the hands of the patient, the patient naturally wants pressure as low as possible but high enough to prevent events.
If the patient can do simple addition and subtraction on a first- or second-grade level and has a full-data machine, the patient would see AHI go up if overtitration occurred and centrals increased, and the patient would then go the other direction to achieve the lowest AHI. It's that simple, that easy.
And that concept has been documented scientifically:
"This study demonstrates that self-titration of CPAP in patients with OSA is as efficacious as manual titration in a sleep laboratory, with similar subjective and objective outcomes, and CPAP compliance. Clearly, for this strategy to be successful, the patient must understand when and how to change the CPAP."--American Journal of Respiratory and Critical Care Medicine, Vol 167. pp. 716-722, (2003) "Can Patients with Obstructive Sleep Apnea Titrate Their Own Continuous Positive Airway Pressure?" by Michael F. Fitzpatrick, Christi E. D. Alloway, Tracy M. Wakeford, Alistair W. MacLean, Peter W. Munt and Andrew G. Day.
http://ajrccm.atsjournals.org/cgi/content/full/167/5/716
Home machines that report AHI will report apneas (whether central or obstructive) as apneas. In fact, home machines happen to be great at catching apneas, as long as leak is under control.
Some newer machines will even differentiate between the two, telling you which ones were likely centrals and which ones were likely obstructives. But that differentiation isn't needed when self-titrating, really. And here's why . . .
If you raise your pressure and your numbers get worse over the next week or two, even just a little bit, you simply lower your pressure back down. In fact, if you raise your pressure and your numbers stay the same over the next week or two, and you don't feel any better either, you simply lower your pressure back down. Some have found that they feel better at a pressure lower than that prescribed, and if the numbers don't get worse and the patient still feels good, that should be fine.
All that being said, it is always best when the doc is on board with what any patient does, so I am not suggesting that anyone out there ignore advice from a doc. I am just a fellow patient passing on what fellow patients with cooperative docs have found has worked for them.
Self-titrating CPAP is much easier, and safer, than a diabetic titrating his own insulin day to day, after all, as most all insulin users have to do.
Some machines use the "forced oscillation technique," or FOT, to estimate likelihood of an event being central, as described in the following white paper from ResMed:
http://www.resmed.com/us/assets/documents/product/s9_series/1013916...
Machines with that capability are available here in the US in the Philips-Respironics PR System One line of machines and in the ResMed S9 line of machines.
Note that the System One calls the likely centrals "clear airway apneas." ( http://advancedeventdetection.respironics.com/waveforms.aspx ) That is a particularly honest way to put it, in my opinion, since it is only the measured status of the airway that the home machines use to judge whether there may have been a central component to the event. That method is not as accurate as using effort belts around a patient's belly and chest, as is done during a nocturnal PSG. That industry-standard, gold-standard method allows for events to be labeled as "mixed," as well. FOT is better than nothing, and a useful thing to do--just not as good as PSG.
I would not base the purchase of a machine on that feature alone, since, as I mentioned earlier, as long as all events are being scored in some consistent way, that is enough trending information to self-titrate, whether the patient knows if any particular apnea is mostly central in nature or not.
Overtitration is a nonissue.
When pressure choices are put in the hands of the patient, the patient naturally wants pressure as low as possible but high enough to prevent events.
If the patient can do simple addition and subtraction on a first- or second-grade level and has a full-data machine, the patient would see AHI go up if overtitration occurred and centrals increased, and the patient would then go the other direction to achieve the lowest AHI. It's that simple, that easy.
And that concept has been documented scientifically:
"This study demonstrates that self-titration of CPAP in patients with OSA is as efficacious as manual titration in a sleep laboratory, with similar subjective and objective outcomes, and CPAP compliance. Clearly, for this strategy to be successful, the patient must understand when and how to change the CPAP."--American Journal of Respiratory and Critical Care Medicine, Vol 167. pp. 716-722, (2003) "Can Patients with Obstructive Sleep Apnea Titrate Their Own Continuous Positive Airway Pressure?" by Michael F. Fitzpatrick, Christi E. D. Alloway, Tracy M. Wakeford, Alistair W. MacLean, Peter W. Munt and Andrew G. Day.
http://ajrccm.atsjournals.org/cgi/content/full/167/5/716
What I meant was that over-titrating is a nonissue in the sense that it is unlikely when pressure tweaks are in the hands of the patient. No patient wants to raise the pressure without a reason. Higher pressure generally is less comfortable. Only if lower numbers or feeling better is the result will a patient raise pressure. If anything, there is a higher risk of under-titration than over-titration, for that reason. Ideally, patients titrate away RERAs by being aware of how rested they feel in the morning.
To stress my position, I think a lab titration is the most valuable thing there is for anyone with OSA. That initial titration is very important, in my opinion, to document how someone reacts to pressures. After that, small tweaks based on weeks worth of data may help how a patient feels, but that doesn't mean ignoring the information from the titration or ignoring doctors. A patient playing a more active role should not prevent the doctor and RT continuing to play their role in the medical team. The ideal situation is mutual respect and teamwork. And the basic schematic outlining the approach of the entire team should be based on a scientific, yet artistic, titration by a highly trained RPSGT. In my opinion.
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