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http://www.vnstherapy.com/depression/indications_for_use.asp

3. WARNINGS — GENERAL

Patients with obstructive sleep apnea (OSA) may have an increase in apneic events during stimulation. Lowering stimulus frequency or prolonging "OFF" time may prevent exacerbation of OSA. Vagus nerve stimulation may also cause new onset sleep apnea in patients who have not previously been diagnosed with this disorder.

Pubmed research study:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576315/

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